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Timing of Operative Debridement for Necrotizing Soft Tissue Infection2015

Type: New Practice Management Guideline (PMG)
Category: Emergency General Surgery
Committee Liaison: Christopher Dodgion, MD, MSPH, MBA


Team leader(s)

Necrotizing soft tissue infections are severe, rapidly progressing infections with an extremely high morbidity and mortality rate. Research has shown that early operative debridement is essential for managing these aggressive infections. However, to date, there is no consensus regarding the optimal timing of repeat debridements after the initial operation. The purpose of this PMG would be to define whether the timing of re-operation (early vs late) has an impact on patient outcomes. PICO QUESTION 1: P: Patients with Necrotizing soft tissue infection I: Timing for re-operation - early (less than 12 hours) C: versus late (greater than 12 hours) O: Overall mortality PICO QUESTION 2 P: Patients with Necrotizing soft tissue infection I: Timing for re-operation - early (less than 12 hours) C: versus late (greater than 12 hours) O: Organ failure

Guidelines Volunteers
Eileen Bulger, MD
Christopher Dodgion, MD
Paula Ferrada, MD
Mansoor Khan, MD
Kosar Khwaja, MD
Anirudh Kohli, MD
Michele M. Loor, MD
Caleb Mentzer, MD
Bryce Robinson, MD, MS
Jessica Summers, MD
Brian Williams, MD
Daniel Dante Yeh, MD
James Yon, MD


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