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Burn Wound Care

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Toxic epidermal necrolysis. A step forward in treatment.
Heimbach DM, Engrav LH, Marvin JA, Harnar TJ, Grube BJ.
JAMA. 1987 Apr 24;257(16):2171-5.

Rationale for inclusion: First paper describing use of porcine xenograft for the treatment of SJS/TEN. Authors found this treatment algorithm was associated with a massive decrease in mortality. 

CAVEAT: Single center, non-randomized

Citations  - To review the number of citations for this landmark paper, visit Google Scholar.

Clinical experience with viable frozen human skin and a frozen skin bank.
Bondoc CC, Burke JF.
Ann Surg. 1971 Sep;174(3):371-82.

Rationale for inclusion: First paper demonstrating that human skin could be frozen and banked both for allo and autograft without diminishing viability. 

CAVEAT: Case study, largely opinion paper

Citations  - To review the number of citations for this landmark paper, visit Google Scholar.

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