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Cholangitis

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Delayed endoscopic retrograde cholangiopancreatography is associated with persistent organ failure in hospitalised patients with acute cholangitis.
Lee F, Ohanian E, Rheem J, Laine L, Che K, Kim JJ.
Aliment Pharmacol Ther. 2015 Jul;42(2):212-20.

Rationale for inclusion: Delay in the management of acute cholangitis can increase morbidity and mortality. The ability to decompress via ERCP improves outcome. The authors demonstrate that a delay of >48 hours in performing ERCP even with ongoing antibiotic treatment, worsened outcome thereby emphasizing the need for timely intervention with these patients. 

Citations - 12 (as of July 2017)

Evaluation of Antibiotic Use to Prevent Post-Endoscopic Retrograde Cholangiopancreatography Pancreatitis and Cholangitis.
Ishigaki T, Sasaki T, Serikawa M, Kobayashi K, Kamigaki M, Minami T, Okazaki A, Yukutake M, Ishii Y, Kosaka K, Mouri T, Yoshimi S, Chayama K.
Hepatogastroenterology. 2015 Mar-Apr;62(138):417-24.

Rationale for inclusion: The authors conclude that addition of prophylactic antibiotics do not reduce risk of cholangitis after ERCP.

Citations - 4 (as of July 2017)

TG13 antimicrobial therapy for acute cholangitis and cholecystitis.
Gomi H, Solomkin JS, Takada T, Strasberg SM, Pitt HA, Yoshida M, Kusachi S, Mayumi T, Miura F, Kiriyama S, Yokoe M, Kimura Y, Higuchi R, Windsor JA, Dervenis C, Liau KH, Kim MH; Tokyo Guideline Revision Committee.
J Hepatobiliary Pancreat Sci. 2013 Jan;20(1):60-70.

Rationale for inclusion: This 2013 Tokyo Guidelines update provides recommendations for antimicrobial therapy.

Citations - 77 (as of July 2017)

 

TG13 flowchart for the management of acute cholangitis and cholecystitis.
Miura F, Takada T, Strasberg SM, Solomkin JS, Pitt HA, Gouma DJ, Garden OJ, Büchler MW, Yoshida M, Mayumi T, Okamoto K, Gomi H, Kusachi S, Kiriyama S, Yokoe M, Kimura Y, Higuchi R, Yamashita Y, Windsor JA, Tsuyuguchi T, Gabata T, Itoi T, Hata J, Liau KH; Tokyo Guidelines Revision Committee.
J Hepatobiliary Pancreat Sci. 2013 Jan;20(1):47-54.

 Rationale for inclusion: This 2013 Tokyo Guidelines update provides a flowchart for the recommended treatment of acute cholangitis stratified by disease severity.

Citations - 133 (as of July 2017)

New diagnostic criteria and severity assessment of acute cholangitis in revised Tokyo Guidelines.
Kiriyama S, Takada T, Strasberg SM, Solomkin JS, Mayumi T, Pitt HA, Gouma DJ, Garden OJ, Büchler MW, Yokoe M, Kimura Y, Tsuyuguchi T, Itoi T, Yoshida M, Miura F, Yamashita Y, Okamoto K, Gabata T, Hata J, Higuchi R, Windsor JA, Bornman PC, Fan ST, Singh H, de Santibanes E, Gomi H, Kusachi S, Murata A, Chen XP, Jagannath P, Lee S, Padbury R, Chen MF; Tokyo Guidelines Revision Committee.
J Hepatobiliary Pancreat Sci. 2012 Sep;19(5):548-56.

Rationale for inclusion: This Tokyo Guidelines 2013 update provides a good evidence-based review of the diagnostic criteria and severity assessment of acute cholangitis.

Citations - 94 (as of July 2017)

Endoscopic biliary drainage for severe acute cholangitis.
Lai EC, Mok FP, Tan ES, Lo CM, Fan ST, You KT, Wong J.
N Engl J Med. 1992 Jun 11;326(24):1582-6.

Rationale for inclusion: This RCT is widely cited as the evidence-base supporting initial endoscopic CBD clearance (as opposed to surgery) for patients with acute cholangitis.

Citations - 589 (as of July 2017)

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