« Back to All

HEME - VTE Prophylaxis

149 pageviews


Antithrombotic Therapy for VTE Disease: CHEST Guideline and Expert Panel Report.
Kearon C, Akl EA, Ornelas J, Blaivas A, Jimenez D, Bounameaux H, Huisman M, King CS, Morris TA, Sood N, Stevens SM, Vintch JRE, Wells P, Woller SC, Moores L.
Chest. 2016 Feb;149(2):315-352.

Rationale for inclusion: These CHEST guidelines serve as the updated recommendations from the prior edition regarding VTE therapy.  Many recommendations are unchanged, with the notable exception of long term therapy. Specifically, dabigatran, rivaroxaban, apixaban, or edoxaban are recommended for long-term VTE treatment over vitamin K antagonists. 

Citations  - To review the number of citations for this landmark paper, visit Google Scholar.

A systematic method for follow-up improves removal rates for retrievable inferior vena cava filters in a trauma patient population.
Irwin E, Byrnes M, Schultz S, Chipman J, Beal A, Ahrendt M, Beilman G, Croston JK.
J Trauma. 2010 Oct;69(4):866-9.

Rationale for inclusion: A patient safety approach to IVC filter manegment to ensure timely removal when no longer indicated

Citations  - To review the number of citations for this landmark paper, visit Google Scholar.

Standard prophylactic enoxaparin dosing leads to inadequate anti-Xa levels and increased deep venous thrombosis rates in critically ill trauma and surgical patients.
Malinoski D, Jafari F, Ewing T, Ardary C, Conniff H, Baje M, Kong A, Lekawa ME, Dolich MO, Cinat ME, Barrios C, Hoyt DB.
J Trauma. 2010 Apr;68(4):874-80.

Rationale for inclusion: Standard lovenox dosing may not be adaquate; this paper describes the use of tracking Xa levels

Citations  - To review the number of citations for this landmark paper, visit Google Scholar.

Thromboelastography as a better indicator of hypercoagulable state after injury than prothrombin time or activated partial thromboplastin time.
Park MS, Martini WZ, Dubick MA, Salinas J, Butenas S, Kheirabadi BS, Pusateri AE, Vos JA, Guymon CH, Wolf SE, Mann KG, Holcomb JB.
J Trauma. 2009 Aug;67(2):266-75; discussion 275-6.

Rationale for inclusion: Excellent description on discerning hypercoagulable states using TEG

Citations  - To review the number of citations for this landmark paper, visit Google Scholar.

The practice of venous thromboembolism prophylaxis in the major trauma patient.
Nathens AB, McMurray MK, Cuschieri J, Durr EA, Moore EE, Bankey PE, Freeman B, Harbrecht BG, Johnson JL, Minei JP, McKinley BA, Moore FA, Shapiro MB, West MA, Tompkins RG, Maier RV.
J Trauma. 2007 Mar;62(3):557-62; discussion 562-3.

Rationale for inclusion: Avery Nathans paper on VTE prophylaxis following major trauma

Citations  - To review the number of citations for this landmark paper, visit Google Scholar.

« Back to All

Eastern Association for the Surgery of Trauma

Contact
633 N. Saint Clair Street, Suite 2400 Chicago, IL 60611-3295 (312) 202-5508 phone (312) 202-5064 fax managementoffice@east.org
Stay connected to EAST
Support EAST
  • AmazonSmiel
Donate Now