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Renal - Electrolytes

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Fluctuations in serum sodium level are associated with an increased risk of death in surgical ICU patients.
Sakr Y, Rother S, Ferreira AM, Ewald C, Dünisch P, Riedemmann N, Reinhart K.
Crit Care Med. 2013 Jan;41(1):133-42.

Rationale for inclusion: Dysnatremia associated with increased mortality risk in SICU.

Citations  - To review the number of citations for this landmark paper, visit Google Scholar.

Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Yunos NM, Bellomo R, Hegarty C, Story D, Ho L, Bailey M.
JAMA. 2012 Oct 17;308(15):1566-72.

Rationale for inclusion: Chloride restrictive IVF associated with decreased risk of AKI and CRRT.

Citations  - To review the number of citations for this landmark paper, visit Google Scholar.

Development of ionized hypomagnesemia is associated with higher mortality rates.
Soliman HM, Mercan D, Lobo SS, Mélot C, Vincent JL.
Crit Care Med. 2003 Apr;31(4):1082-7.

Rationale for inclusion: Hypomagnesemia associated with high mortality and sepsis.

Citations  - To review the number of citations for this landmark paper, visit Google Scholar.

Hypocalcemia: a pervasive metabolic abnormality in the critically ill.
Zivin JR, Gooley T, Zager RA, Ryan MJ.
Am J Kidney Dis. 2001 Apr;37(4):689-98.

Rationale for inclusion: Prevalence and effect of hypocalcemia in the ICU. .

Citations  - To review the number of citations for this landmark paper, visit Google Scholar.

Hypomagnesemia and hypophosphatemia at admission in patients with severe head injury.
Polderman KH, Bloemers FW, Peerdeman SM, Girbes AR.
Crit Care Med. 2000 Jun;28(6):2022-5.

Rationale for inclusion: Electrolytes disturbances in TBI.

Citations  - To review the number of citations for this landmark paper, visit Google Scholar.

Hypernatremia in the critically ill is an independent risk factor for mortality.
Lindner G, Funk GC, Schwarz C, Kneidinger N, Kaider A, Schneeweiss B, Kramer L, Druml W.
Am J Kidney Dis. 2007 Dec;50(6):952-7.

Rationale for inclusion: Prevalence of hypernatremia and its impact on mortality.

Citations  - To review the number of citations for this landmark paper, visit Google Scholar.

Pulmonary complications of hyponatremic encephalopathy. Noncardiogenic pulmonary edema and hypercapnic respiratory failure.
Ayus JC, Arieff AI.
Chest. 1995 Feb;107(2):517-21.

Rationale for inclusion: Respiratory failure due to hyponatremic encephalopathy - noncardiogenic edema and hypercarpnia.

Citations  - To review the number of citations for this landmark paper, visit Google Scholar.

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