- Pathophysiologic response to severe burn injury.
- Jeschke MG, Chinkes DL, Finnerty CC, Kulp G, Suman OE, Norbury WB, Branski LK, Gauglitz GG, Mlcak RP, Herndon DN.
- Ann Surg. 2008 Sep;248(3):387-401.
Rationale for inclusion: Burn patients show many markers of a hyper-inflammatory state.
Citations - 191 (as of July 2017)
- Reversal of catabolism by beta-blockade after severe burns.
- Herndon DN, Hart DW, Wolf SE, Chinkes DL, Wolfe RR.
- N Engl J Med. 2001 Oct 25;345(17):1223-9.
Rationale for inclusion: Describes use of propranolol in children with burn injuries to attenuate hyper-metabolism and reverse muscle-protein catabolism.
Citations - 467 (as of July 2017)
- Association of hyperglycemia with increased mortality after severe burn injury.
- Gore DC, Chinkes D, Heggers J, Herndon DN, Wolf SE, Desai M.
- J Trauma. 2001 Sep;51(3):540-4.
Rationale for inclusion: Poor glucose control in pediatric burn patients is associated with poor outcomes including skin graft take, bacteremia, and mortality.
Citations - 476 (as of July 2017)
- Objective estimates of the probability of death from burn injuries.
- Ryan CM, Schoenfeld DA, Thorpe WP, Sheridan RL, Cassem EH, Tompkins RG.
- N Engl J Med. 1998 Feb 5;338(6):362-6.
Rationale for inclusion: Describes 3 risk factors (age greater than 60 years, more than 40 percent of body-surface area burned, and inhalation injury) to help predict risk of mortality after burns.
Citations - 626 (as of July 2017)
- Use of an acellular allograft dermal matrix (AlloDerm) in the management of full-thickness burns.
- Wainwright DJ.
- Burns. 1995 Jun;21(4):243-8.
Rationale for inclusion: Describes use of human allograft skin for treatment of a full-thickness burn injury.
Citations - 849 (as of July 2017)
- Permanent coverage of large burn wounds with autologous cultured human epithelium.
- Gallico GG 3rd, O'Connor NE, Compton CC, Kehinde O, Green H.
- N Engl J Med. 1984 Aug 16;311(7):448-51.
Rationale for inclusion: Well-cited, use of cultured epithelium to cover burn wounds with results similar to split thickness skin grafting.
Citations - 1300 (as of July 2017)
- Successful use of a physiologically acceptable artificial skin in the treatment of extensive burn injury.
- Burke JF, Yannas IV, Quinby WC Jr, Bondoc CC, Jung WK.
- Ann Surg. 1981 Oct;194(4):413-28.
Rationale for inclusion: Describes use of an artificial skin substitute for grafting to burn wounds.
Citations - 1141 (as of July 2017)