« Back to All

GI - Liver: Critical Care in Hepatic Failure

3 pageviews


Suboptimal Implementation of Evidence-based Therapy for Acute Variceal Hemorrhage: A Systematic Review of Observational Studies.
Tapper EB, Beste L, Curry M, Bonder A, Waljee A, Saini S.
Clin Gastroenterol Hepatol. 2017 Feb 27. pii: S1542-3565(17)30198-2.

Rationale for inclusion: This is a survey that demonstrates "suboptimal implementation" of the evidence-based practices for critical management of variceal bleeding.

Citations  - To review the number of citations for this landmark paper, visit Google Scholar.

Advances in management and prognostication in critically ill cirrhotic patients.
Karvellas CJ, Bagshaw SM.
Curr Opin Crit Care. 2014 Apr;20(2):210-7

Rationale for inclusion: This is a really comprehensive survey of the latest therapies for cirrhotic patients presenting with sepsis, variceal bleeds, hepatorenal syndrome, as well as scoring systems.  The CANONIC, HELIOS, and RELIEF trials are discussed.

Citations  - To review the number of citations for this landmark paper, visit Google Scholar.

Acute-on-chronic liver failure is a distinct syndrome that develops in patients with acute decompensation of cirrhosis.
Moreau R, Jalan R, Gines P, Pavesi M, Angeli P, Cordoba J, Durand F, Gustot T, Saliba F, Domenicali M, Gerbes A, Wendon J, Alessandria C, Laleman W, Zeuzem S, Trebicka J, Bernardi M, Arroyo V; CANONIC Study Investigators of the EASL–CLIF Consortium.
Gastroenterology. 2013 Jun;144(7):1426-37, 1437.e1-9.

Rationale for inclusion: This article established the criteria and staging scores for ACLF - this is a paper from the EASL-CLIF consortium.

Citations  - To review the number of citations for this landmark paper, visit Google Scholar.

« Back to All