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Multiple Rib Fractures

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A multicenter, prospective, controlled clinical trial of surgical stabilization of rib fractures in patients with severe, nonflail fracture patterns (Chest Wall Injury Society NONFLAIL)
Pieracci FM, Leasia K, Bauman Z, Eriksson EA, Lottenberg L, Majercik S, Powell L, Sarani B, Semon G, Thomas B, Zhao F, Dyke C, Doben AR.
J Trauma Acute Care Surg. 2020 Feb;88(2):249-257.

Rationale for inclusion: Multicenter clinical trial comparing surgical stabilization of rib fractures to medical management in patients without flail chest.

CAVEAT: Only 23/110 patients in randomized arm, remainder self-selected their treatment group.

Citations  - To review the number of citations for this landmark paper, visit Google Scholar.

A multicenter evaluation of the optimal timing of surgical stabilization of rib fractures.
Pieracci FM, Coleman J, Ali-Osman F, Mangram A, Majercik S, White TW, Jeremitsky E, Doben AR.
J Trauma Acute Care Surg. 2018 Jan;84(1):1-10.

Rationale for inclusion: Observational study using Australian government statistics on deaths caused by firearms (1979-2013) and compared changes in intentional firearm death rates before and after gun legislation reforms in 1996.  After gun law reforms, firearm deaths decreased and there were no mass killings with firearms.

Citations  - To review the number of citations for this landmark paper, visit Google Scholar.

Prospective randomized controlled trial of operative rib fixation in traumatic flail chest.
Marasco SF, Davies AR, Cooper J, Varma D, Bennett V, Nevill R, Lee G, Bailey M, Fitzgerald M.
J Am Coll Surg. 2013 May;216(5):924-32.

Rationale for inclusion:  Prospective, randomized trial comparing operative rib fixation with mechanical ventilation  for flail chest injuries.  

Citations  - To review the number of citations for this landmark paper, visit Google Scholar.

Rib fracture repair: indications, technical issues, and future directions.
Nirula R, Diaz JJ Jr, Trunkey DD, Mayberry JC.
World J Surg. 2009 Jan;33(1):14-22.

Rationale for inclusion:  A widely cited and comprehensive review regarding operative rib fixation.

Citations  - To review the number of citations for this landmark paper, visit Google Scholar.

Epidural analgesia improves outcome after multiple rib fractures.
Bulger EM, Edwards T, Klotz P, Jurkovich GJ.
Surgery. 2004 Aug;136(2):426-30.

Rationale for inclusion: Prospective, randomized trial compared epidural analgesia versus IV opioids for rib fractures.  The use of epidural analgesia improved mechanical ventilation duration and pneumonia rates.

Citations  - To review the number of citations for this landmark paper, visit Google Scholar.

A comprehensive analysis of traumatic rib fractures: morbidity, mortality and management.
Sirmali M, Türüt H, Topçu S, Gülhan E, Yazici U, Kaya S, Tastepe I.
Eur J Cardiothorac Surg. 2003 Jul;24(1):133-8.

Rationale for inclusion: Large retrospective study correlating age and number of rib fractures with outcomes.

Citations  - To review the number of citations for this landmark paper, visit Google Scholar.

Morbidity from rib fractures increases after age 45.
Holcomb JB, McMullin NR, Kozar RA, Lygas MH, Moore FA.
J Am Coll Surg. 2003 Apr;196(4):549-55.

Rationale for inclusion: Retrospective cohort study of 171 patients with rib fractures that were compared with respect to number of rib fractures and age.

Citations  - To review the number of citations for this landmark paper, visit Google Scholar.

Elderly trauma patients with rib fractures are at greater risk of death and pneumonia.
Bergeron E, Lavoie A, Clas D, Moore L, Ratte S, Tetreault S, Lemaire J, Martin M.
J Trauma. 2003 Mar;54(3):478-85.

Rationale for inclusion: Mortality was greater (19%) in patients >65 years with multiple rib fractures.

Citations  - To review the number of citations for this landmark paper, visit Google Scholar.

Surgical stabilization of internal pneumatic stabilization? A prospective randomized study of management of severe flail chest patients.
Tanaka H, Yukioka T, Yamaguti Y, Shimizu S, Goto H, Matsuda H, Shimazaki S.
J Trauma. 2002 Apr;52(4):727-32; discussion 732.

Rationale for inclusion: Surgical rib fixation was compared with internal pneumatic stabilization in this prospective, randomized trial.

Citations  - To review the number of citations for this landmark paper, visit Google Scholar.

The morbidity and mortality of rib fractures.
Ziegler DW, Agarwal NN.
J Trauma. 1994 Dec;37(6):975-9.

Rationale for inclusion: An initial study documenting the morbidity and mortality associated with rib fractures.

Citations  - To review the number of citations for this landmark paper, visit Google Scholar.

Management of flail chest without mechanical ventilation.
Trinkle JK, Richardson JD, Franz JL, Grover FL, Arom KV, Holmstrom FM.
Ann Thorac Surg. 1975 Apr;19(4):355-63.

Rationale for inclusion: Challenged convention by comparing patient with flail chests who underwent intubation and mechanical ventilation versus treatment of the underlying pulmonary contusion alone.

Citations  - To review the number of citations for this landmark paper, visit Google Scholar.

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