Completed Studies

Includes studies that have reached completion and have provided EAST information regarding abstract presentation and manuscript acceptance and have corresponded that the study is complete. All information (e.g. study proposals) are available upon request.

Completed 2021 Studies

Wound Management in Emergency Colorectal Surgery: To Close or Not to Close?

Principal Investigators & Contact Information:

Cristina Barbosa Feather, MD, MHS, FACS

Anne Arundel Medical Center

cfeather@aahs.org 

J. Robert Klune, MD, MBA, FACS (Co-primary investigator)

Justin Turcotte, Ph.D., MBA (Co-primary investigator)


Development and Validation of a Prehospital Triage Model for the Severely Injured Trauma Patient

Principal Investigator & Contact Information:

Rachel S. Morris, MD

Medical College of Wisconsin

ramorris@mcw.edu

Christopher J Tignanelli, MD (Co-primary investigator)

Biesboer EA, Pokrzywa CJ, Karam BS, Chen B, Szabo A, Teng BQ, Bernard MD, Bernard A, Chowdhury S, Hayudini AE, Radomski MA, Doris S, Yorkgitis BK, Mull J, Weston BW, Hemmila MR, Tignanelli CJ, de Moya MA, Morris RS. Prospective validation of a hospital triage predictive model to decrease undertriage: an EAST multicenter study. Trauma Surg Acute Care Open. 2024 May 2;9(1):e001280. doi: 10.1136/tsaco-2023-001280. PMID: 38737811; PMCID: PMC11086287.

Link


Intravascular access in hypotensive trauma patients: an Eastern Association for the Surgery of Trauma multicenter prospective observational trial using trauma video review

Principal Investigators & Contact Information:

Ryan P. Dumas MD, FACS

UTSW Medical Center / Parkland Memorial Hospital

ryan.dumas@utsouthwestern.edu 

Michael A. Vella, MD (Co-primary investigator)


Outcomes of Early Initiation of Venous Thromboembolism Prophylaxis in Isolated Traumatic Brain Injuries

Principal Investigators & Contact Information:

Asanthi Ratnasekera DO FACS & Daniel Kim MD

Crozer

ashanthi27@hotmail.com 

Ammar Humayun MD (Co-primary investigator)

Sirivan Seng MD (Co-primary investigator)

Alexander Papa BS (Co-primary investigator)

Danielle Lapoint BS (Co-primary investigator)

Sandra Durgin MSN, TCRN (Co-primary investigator)

Paula Ferrada MD FACS (Mentor)


Completed 2020 Studies

Prospective comparison of a short versus long chest tube water seal trial for traumatic pneumothorax

Principal Investigator & Contact Information:

Stephen Varga, MD

Inova Fairfax Hospital

Stephen.varga@inova.org 


Defining Outcomes after Ultra-Massive Transfusion in the Modern Era of Balanced and Goal-Directed Resuscitation

Principal Investigators & Contact Information:

Zachary A. Matthay, MD

UCSF - San Francisco General Hospital

Zachary.Matthay@ucsf.edu

Lucy Z. Kornblith, MD

UCSF - San Francisco General Hospital

lucy.kornblith@ucsf.edu

Rachael A. Callcut, MD, MSPH, FACS

UCSF - San Francisco General Hospital

rachael.callcut@ucsf.edu


Management of Acute Appendicitis and Cholecystitis During the COVID-19 Pandemic: An EAST Multicenter Contemporaneous Cohort Study

Principal Investigator & Contact Information:

Rondi B. Gelbard, MD

University of Alabama at Birmingham

rgelbard@uabmc.edu


EAST Multicenter Trial: Damage Control Thoracotomy (DCT) in Thoracic Trauma

Principal Investigator & Contact Information:

Ashley Meagher, MD MPH

Indiana University School of Medicine

ashmeagh@iu.edu 


Prehospital end-tidal carbon dioxide is predictive of death and massive transfusion in injured patients: An Eastern Association for Surgery of Trauma multicenter trial

Principal Investigator & Contact Information:

Eric M. Campion MD

Denver Health Medical Center /University of Colorado, Anschutz

Eric.Campion@dhha.org 

 doi: 10.1097/TA.0000000000003447.

Link


Use of Andexanet Alfa versus KCentra for Reversal of Direct Oral Factor Xa Inhibitors: An EAST Multicenter Study Proposal

Principal Investigators & Contact Information:

Jordan M. Estroff, MD, FACS

George Washington University

jestroff@mfa.gwu.edu

Babak Sarani, MD, FACS, FCCM

George Washington University

bsarani@mfa.gwu.edu


Medical Management of Grade 1 and 2 Splenic Injuries with active extravasation

Principal Investigators & Contact Information:

Kristen Spoor, MD

Prisma Health’s Greenville Memorial Hospital

kristen.spoor@prismahealth.org

John Cull, MD, FACS

Greenville Health System

jcull@ghs.org


Completed 2019 Studies

Prospective Multicenter Derivation and Validation of a NECROtizing Soft tissue Infection Score (NECROSIS)

Principal Investigator & Contact Information:

Dennis Y. Kim, MD

Harbor-UCLA Medical Center 

dennisyongkim@gmail.com 

Kim, Dennis Y. MD, MMEd, FACS, FRCSC1; Iavasile, Amanda2; Kaji, Amy H. MD, PhD3; Nahmias, Jeffry MD, MHPE4; Grigorian, Areg MD5; Mukherjee, Kaushik MD, MSCI6; Penaloza, Liz MD6; Posluszny, Joseph MD7; Logan, Charles D. MD8; Michelin, Erika MD9; Serena, Thomas DO9; Sahr, Sheryl MD, MS10; Bekdache, Khaldoun MD11; Stoddard, Nathan12; Choudhry, Asad MD13; Zerna Encalada, Ronald MD13; Saltzman, Darin MD, PhD14; Padilla, Reynaldo BA14; Truitt, Michael MD15; Grossman Verner, Heather MS16; Hunt, Darren MD17; Purvis, Victoria MD17; Ross, Samuel Wade MD, MPH18; Mallah, Mike M. MD18; Dultz, Linda MD, MPH19; Kuhlenschmidt, Kali MD19; Mentzer, Caleb J. DO20; Lonkar, Adwait DO20; Chang, Grace MD21; Lemon, Brittney DO21; de Virgilio, Christian MD22. Prospective derivation and validation of a NECROtizing Soft tissue InfectionS (NECROSIS) score: An EAST multicenter trial. Journal of Trauma and Acute Care Surgery ():10.1097/TA.0000000000004374, May 9, 2024. | DOI: 10.1097/TA.0000000000004374
Link


Anticoagulation in Emergency General Surgery: Who bleeds more? The ACES TRIAL

Principal Investigator & Contact Information:

Lindsay O'Meara, CRNP

University of Maryland Medical Center

lomeara@umm.edu 


Brain vs. Bone: Does fracture fixation technique influence outcomes in patients with traumatic brain injury (TBI)?

Principal Investigator & Contact Information:

Mira Ghneim, MD

R Adams Cowley Shock Trauma Center 

mira.ghneim@som.umaryland.edu 


A Comprehensive and Collaborative Review of the Use of Whole Blood at Trauma Centers in the United States

Principal Investigators & Contact Information:

Joshua P. Hazelton, DO, FACS, FACOS

Penn State Hershey Medical Center

jhazelton@pennstatehealth.psu.edu

Anna Ssentongo, MPH

Penn State Hershey Medical Center

assentongo@pennstatehealth.psu.edu


Outcomes after acute care surgery and trauma care in incarcerated individuals: a prospective observational trial

Principal Investigator & Contact Information:

Rebecca Maine, MD

University of Washington

rmaine@uw.edu

 doi: 10.1097/TA.0000000000003614. Epub 2022 Apr 1.

Link


Sedation and paralytic use in open abdomen patients-results from the EAST SLEEP Survey

Principal Investigator & Contact Information:

Kaushik Mukherjee MD MSCI FACS

Loma Linda University Medical Center 

KMukherjee@llu.edu

 doi: 10.1016/j.surg.2019.07.017. Epub 2019 Sep 6.

Link


An Eastern Association for the Surgery of Trauma multicenter trial examining prehospital procedures in penetrating trauma patients

Principal Investigator & Contact Information:

Sharven Taghavi, MD

Tulane University School of Medicine

staghavi@tulane.edu

 doi: 10.1097/TA.0000000000003151.

Link


Completed 2018 Studies

The Time Has Come To Question the ABCs Priorities of Trauma: Circulation First a Multicenter Prospective observational trial

Principal Investigator & Contact Information:

Paula Ferrada, MC, FACS

Virginia Commonwealth University 

pfanand@gmail.com 

Ferrada, P., García, A., Duchesne, J. et al. Comparing outcomes in patients with exsanguinating injuries: an Eastern Association for the Surgery of Trauma (EAST), multicenter, international trial evaluating prioritization of circulation over intubation (CAB over ABC). World J Emerg Surg 19, 15 (2024). https://doi.org/10.1186/s13017-024-00545-8

Link


Characteristics of survivors of civilian public mass shootings: An Eastern Association for the Surgery of Trauma multicenter study

Principal Investigator & Contact Information:

Babak Sarani, MD

George Washington University 

bsarani@mfa.gwu.edu 

Journal of Trauma and Acute Care Surgery: April 2021 - Volume 90 - Issue 4 - p 652-658
doi: 10.1097/TA.0000000000003069
Link


Multicenter Prospective Observational Study of Trauma Patients on Antiplatelet Agents

Principal Investigator & Contact Information:

Brian K. Yorkgitis, DO, FACS

University of Florida- Jacksonville

brian.yorkgitis2@jax.ufl.edu


Outcomes in patients with gunshot wounds to the brain

Principal Investigator & Contact Information:

Robert D. Winfield, M.D., FACS

University of Kansas Medical Center 

rwinfield@kumc.edu 

Link


Contemporary management of traumatic cervical and thoracic esophageal perforation: The results of an Eastern Association for the Surgery of Trauma multi-institutional study

Principal Investigators & Contact Information:

Lauren Raff, MD

UNC School of Medicine

Lauren_Raff@med.unc.edu 

Patrick L Bosarge, MD

University of Arizona College of Medicine - Phoenix

pbosarge@uabmc.edu 

 doi: 10.1097/TA.0000000000002841.

Link


Colorectal resection in emergency general surgery: An EAST multicenter trial

Principal Investigators & Contact Information:

Brittany O. Aicher, MD

University of Maryland Medical Center

baicher@som.umaryland.edu 

Brandon R. Bruns, MD

Capital Region Health, University of Maryland

bbruns@umm.edu 

 doi: 10.1097/TA.0000000000002894.

Link


Timing and volume of crystalloid and blood products in pediatric trauma: An Eastern Association for the Surgery of Trauma multicenter prospective observational study

Principal Investigators & Contact Information:

Richard A. Falcone, Jr, MD, MPH

Cincinnati Children's Hospital

Richard.Falcone@cchmc.org 

Stephanie Polites MD, MPH & Juan Gurria MD

Mayo Clinic

Polites.Stephanie@mayo.edu 

Journal of Trauma and Acute Care Surgery: July 2020 - Volume 89 - Issue 1 - p 36-42

doi: 10.1097/TA.0000000000002702

Link


Prospective validation of the Emergency Surgery Score in emergency general surgery: An Eastern Association for the Surgery of Trauma multicenter study

Principal Investigator & Contact Information:

Haytham Kaafarani, MD, MPH, FACS 

Massachusetts General Hospital 

hkaafarani@mgh.harvard.edu 

Journal of Trauma and Acute Care Surgery: July 2020 - Volume 89 - Issue 1 - p 118-124

doi: 10.1097/TA.0000000000002658

Link


The incidence of venous thromboembolic events in trauma patients after tranexamic acid administration: an EAST multicenter study

Principal Investigators & Contact Information:

Babak Sarani, MD

George Washington University 

bsarani@mfa.gwu.edu 

Lisbi Rivas, MD

lisbi_rivas15@hotmail.com 

 doi: 10.1097/MBC.0000000000000983.

Link


Completed 2017 Studies

Can we be FASTeR? A multicenter study utilizing Right sided roll to improve sensitivity of the FAST

Principal Investigators & Contact Information:

Dr. Seong Lee

slee@mhs.net 


Multicenter prospective observational trial of temporary intravascular shunts for trauma

Principal Investigators & Contact Information:

Mark J. Seamon, MD

Hospital of the University of Pennsylvania 

Mark.Seamon@uphs.upenn.edu

Lily Tung, MD

lilyltung@gmail.com


Current Management of Suspected Retained Common Bile Duct Stones in Gallstone Pancreatitis and Choledocholithiasis

Principal Investigator & Contact Information:

Rondi Gelbard, MD

Emory University School of Medicine 

rgelbard@hotmail.com 

2020 Jul;168(1):62-66. doi: 10.1016/j.surg.2020.04.011. Epub 2020 May 26.

Link


Multicenter Study of the Treatment of Appendicitis in America Acute, Perforated, and Gangrenous (MUSTANG), an EAST Multicenter Study

Principal Investigator & Contact Information:

Daniel Dante Yeh, MD

Ryder Trauma Center 

dxy154@med.miami.edu 

Annals of Surgery: October 28, 2019 - Volume Publish Ahead of Print - Issue - p doi: 10.1097/SLA.0000000000003661

Link


Use of regional analgesia and risk of delirium in older adults with multiple rib fractures: An Eastern Association for the Surgery of Trauma multicenter study

Principal Investigators & Contact Information:

Saman Arbabi M.D., M.P.H., F.A.C.S.

Harborview Medical Center 

sarbabi@uw.edu 

Kathleen O'Connell MD

University of Washington

katmo@u.washington.edu 

 doi: 10.1097/TA.0000000000003258.

Link


EAST multicenter trial of simulation-based team training for pediatric trauma: Resuscitation task completion is highly variable during simulated traumatic brain injury resuscitation

Principal Investigators & Contact Information:

Aaron R. Jensen, MD, Med

Children's Hospital Los Angeles 

arjensenmd@gmail.com 

Jensen et al. EAST multicenter trial of simulation based training for pediatric trauma: resuscitation task completion is highly variable during simulated traumatic brain injury resuscitation. Am J Surg 2020. 219(6):1057-64. PMID 31421895.

Link


Infection after penetrating brain injury—An Eastern Association for the Surgery of Trauma multicenter study

Principal Investigators & Contact Information:

Deborah Stein, MD, MPH

R Adams Cowley Shock Trauma Ctr 

dstein@umm.edu 

Laura Harmon, MD

R Adams Cowley Shock Trauma Ctr  

LauraHarmon@umm.edu  

Journal of Trauma and Acute Care Surgery: July 2019 - Volume 87 - Issue 1 - p 61-67

doi: 10.1097/TA.0000000000002327

Link


Completed 2016 Studies

Reducing Routine Phlebotomy in Stable Liver and Splenic Injuries

Principal Investigator & Contact Information:

Jose Prince, MD

jprince@nshs.edu 

 doi: 10.1016/j.jpedsurg.2019.04.021. Epub 2019 May 6.

Link


Anticoagulation therapy in patients with traumatic brain injury: An Eastern Association for the Surgery of Trauma multicenter prospective study

Principal Investigator & Contact Information:

Kazuhide Matsushima, MD

LAC+USC Medical Center, University of Southern California

kazuhide.matsushima@med.usc.edu

Surgery. 2020 Sep 12;S0039-6060(20)30512-2. doi: 10.1016/j.surg.2020.07.040. Online ahead of print.

Link


Blunt small bowel perforation (SBP): An Eastern Association for the Surgery of Trauma multicenter update 15 years later

Principal Investigators & Contact Information:

Samir M Fakhry M.D. (Senior Investigator)

samfak7@gmail.com 

Ahmed Allawi, MD (Co-Investigator)

Medical University of South Carolina 

allawi@musc.edu 

Journal of Trauma and Acute Care Surgery: April 2019 - Volume 86 - Issue 4 - p 642-650

doi: 10.1097/TA.0000000000002176

Link


EAST multicenter trial on targeted temperature management for hanging-induced cardiac arrest

Principal Investigators & Contact Information:

Deborah Stein, MD (Senior Investigator) & Cindy Hsu, MD, PhD

R Adams Cowley Shock Trauma Ctr 

chsu1012@gmail.com 

Journal of Trauma and Acute Care Surgery: July 2018 - Volume 85 - Issue 1 - p 37-47

doi: 10.1097/TA.0000000000001945

Link


Completed 2015 Studies

Prospective Multi-Institutional Evaluation of the Management of Cholecystostomy

Principal Investigators & Contact Information:

Nathaniel Poulin, MD

The Brody School of Medicine at ECU 

poulinn@ecu.edu

Eric A. Toschlog, MD, FACS, FCCM 

East Carolina University 

toschloge@ecu.edu


Multi-institutional, prospective, observational study comparing the Gastrografin challenge versus standard treatment in adhesive small bowel obstruction

Principal Investigator & Contact Information:

Martin D. Zielinski, MD, FACS

Mayo Clinic 

zielinski.martin@mayo.edu

Journal of Trauma and Acute Care Surgery: July 2017 - Volume 83 - Issue 1 - p 47-54

doi: 10.1097/TA.0000000000001499

Link


Predictors of Retained Hemothorax in Trauma Results of an EAST Multi-Institutional Trial

Principal Investigator & Contact Information:

Jeremy W. Cannon, MD, SM, FACS

Perelman School of Medicine at the University of Pennsylvania

jeremy.cannon@uphs.upenn.edu

Priya S. Prakash, MD (assisting) 

pprakash@surgery.bsd.uchicago.edu

Journal of Trauma and Acute Care Surgery: July 8, 2020 - Volume Publish Ahead of Print - Issue -

doi: 10.1097/TA.0000000000002881

Link


Screening for Harassment, Abuse, and Discrimination among Surgery Residents: An EAST Multicenter Trial

Principal Investigator & Contact Information:

Rondi Gelbard, MD

Emory University School of Medicine 

rgelbar@emory.edu

Fitzgerald CA, Smith RN, Luo-Owen X, et al. Screening for Harassment, Abuse, and Discrimination among Surgery Residents: An EAST Multicenter Trial. Am Surg. 2019;85(5):456-461.

Link


Can acute care surgeons perform  while fatigued? An EAST multicenter study

Principal Investigator & Contact Information:

Kevin M. Schuster, MD

Yale School of Medicine 

kevin.schuster@yale.edu

Journal of Trauma and Acute Care Surgery: September 2018 - Volume 85 - Issue 3 - p 476-484

doi: 10.1097/TA.0000000000001975

Link


Platelet Transfusion Does Not Improve Outcomes in Brain Injured Patients on Antiplatelet Therapy

Principal Investigator & Contact Information:

Babak Sarani, MD, FACS, FCCM

George Washington University 

bsarani@mfa.gwu.edu

Jeremy L Holzmacher, Cassandra Reynolds, Mayur Patel, Patrick Maluso, Seth Holland, Nathaniel Gamsky, Henry Moore, Elizabeth Acquista, Matthew Carrick, Richard Amdur, Heather Hancock, Michael Metzler, Julie Dunn & Babak Sarani (2018) Platelet transfusion does not improve outcomes in patients with brain injury on antiplatelet therapy, Brain Injury, 32:3, 325-330, DOI: 10.1080/02699052.2018.1425804

Link


Universal screening for intimate partner and sexual violence in trauma patients
An EAST multicenter trial

Principal Investigator & Contact Information:

Tanya L. Zakrison, MD, MPH, FRCSC, FACS

Miller School of Medicine 

tzakrison@med.miami.edu

Journal of Trauma and Acute Care Surgery: July 2017 - Volume 83 - Issue 1 - p 105-110

doi: 10.1097/TA.0000000000001495

Link


Loop ileostomy versus total colectomy as surgical treatment for Clostridium difficileassociated disease An Eastern Association for the Surgery of Trauma multicenter trial

Principal Investigators & Contact Information:

Paula Ferrada, MD

Virginia Commonwealth University 

pferrada@mcvh-vcu.edu

Rachael Callcut, MD, MSPH, FACS 

UCSF 

callcutr@sfghsurg.ucsf.edu

Journal of Trauma and Acute Care Surgery: July 2017 - Volume 83 - Issue 1 - p 36-40

doi: 10.1097/TA.0000000000001498

Link


Incompatible type A plasma transfusion in patients requiring massive transfusion protocol
Outcomes of an Eastern Association for the Surgery of Trauma multicenter study

Principal Investigator & Contact Information:

Andrew C. Bernard, MD

Univ of Kentucky College of Medicine 

andrew.bernard@uky.edu

Journal of Trauma and Acute Care Surgery: July 2017 - Volume 83 - Issue 1 - p 25-29

doi: 10.1097/TA.0000000000001532

Link