Active Multicenter Trials - Currently Enrolling Centers

These EAST Multicenter Trials are current active and enrolling centers.  These studies are in the development, enrollment, and/or publication process.  Interested in joining a study?  Complete an EAST Center Sign-Up Form found here.

2026 EAST Multicenter Trials

• PRECISE- AAPT: PRagmatic Evaluation of CT In StablE Anterior Abdominal Penetrating Trauma: An EAST Multicenter Trial

• POCOBI: Postoperative Cystography for Operative Bladder Injuries Study, An EAST Multicenter Trial

• Strategies for Thromboprophylaxis Outcomes and Prevention of Venous ThromboEmbolism in EGS (STOP-VTE-EGS); An EAST Prospective Observational Multicenter Trial

2025 EAST Multicenter Trials

• Direct Peritoneal Resuscitation in Emergency General Surgery: An EAST Multicenter Trial

• Evaluation of Triclosan-Coated Barbed Suture Following Emergency Laparotomy: An EAST Multicenter Retrospective and Prospective Cohort Study

• Optimizing Venous Thromboembolism Prophylaxis (VTEp) in Patients Who Have Sustained Operative Spinal Trauma

• Pediatric Intracranial Gunshot Wounds: An EAST Multicenter Study

• Anti Factor Xa Monitoring of Venous Thromboembolism Prophylaxis in Emergency General Surgery Patients: A Prospective Multicenter Study

2024 EAST Multicenter Trials

• Standard Thromboelastography Protocols May Fail to Identify Coagulopathy in Hypothermic
  Trauma Patients – An EAST Multicenter Study

2022 EAST Multicenter Trials

• Prospective Observational Trial Examining Nationwide Trends of Aggressive Resuscitation Protocols for Catastrophic Brain Injuries

2021 EAST Multicenter Trials

• PUSH IT: Preventing Unnecessary Surgeon Holds on Ingestion for Tracheostomy

2020 EAST Multicenter Trials

• Operative Versus Non-Operative Management for Appendicitis with Abscess or Phlegmon: An EAST Prospective Randomized Multicenter Trial

2018 EAST Multicenter Trial

• A Multi-Institutional Cluster Randomized Trial Comparing Standard vs. Extended Venothromboembolic Prophylaxis After Major Trauma

2016 EAST Multicenter Trials

• Mortality Analysis of Trauma Patients Repatriated to Non-Trauma Managed Care Institutions