Active Multicenter Trials - Currently Enrolling Centers

These EAST Multicenter Trials are current active and enrolling centers.  These studies are in the development, enrollment, and/or publication process.  Interested in joining a study?  Complete an EAST Center Sign-Up Form found here.

2024 EAST Multicenter Trials

• Skin Closure After Infected Laparotomy (SCAIL) – An EAST Multicenter Study

• Palliative Care in the Trauma ICU (PiCIT) Trial

• Standard Thromboelastography Protocols May Fail to Identify Coagulopathy in Hypothermic
  Trauma Patients – An EAST Multicenter Study

• Defining Outcomes of Early vs. Delayed Cholecystectomy for Perforated Cholecystitis

• Robotic Acute Care Surgery Utilization and Outcomes: An EAST Prospective, Observational Propensity Matched Multicenter Trial

2023 EAST Multicenter Trials

• Mental Health Screening and Referral: Evaluating Trauma Centers Protocols and Patient Outcomes

• Mixed-Methods Analysis of Care Variation in Severe Traumatic Brain Injury

• Evaluation of Short versus Extended Duration Antibiotic Therapy on Outcomes in Necrotizing Soft Tissue Infection (DATa-NSTI Trial)

• Multi-Center Study of Universal CTA Necks for Major Blunt Trauma Patients

2022 EAST Multicenter Trials

• The Utility of Serial Hemoglobin Monitoring in Non-Operative Management of Blunt Splenic Injury

• Prospective Observational Trial Examining Nationwide Trends of Aggressive Resuscitation Protocols for Catastrophic Brain Injuries

2021 EAST Multicenter Trials

• PUSH IT: Preventing Unnecessary Surgeon Holds on Ingestion for Tracheostomy

• Radiographic Evaluation of Delayed Solid Organ Complications (REDSOC) Study

• Contemporary Management of Right Upper Quadrant Gunshot Wounds

2020 EAST Multicenter Trials

• Impact of Coronavirus Disease 2019 on Trauma Center Volume and Resources: An EAST MCT

• Surgical Critical Care During COVID-19 Pandemic

• Intermediate Health and Social Outcomes following participation in Hospital Based Violence Intervention

• Operative Versus Non-Operative Management for Appendicitis with Abscess or Phlegmon: An EAST Prospective Randomized Multicenter Trial

2018 EAST Multicenter Trial

• A Multi-Institutional Cluster Randomized Trial Comparing Standard vs. Extended Venothromboembolic Prophylaxis After Major Trauma

2016 EAST Multicenter Trials

• Mortality Analysis of Trauma Patients Repatriated to Non-Trauma Managed Care Institutions